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1.
Environ Geochem Health ; 2022 Nov 11.
Article in English | MEDLINE | ID: covidwho-20236382

ABSTRACT

The mean mass concentrations of black carbon (BC), biomass burning (BC)bb, and fossil fuel combustion (BC)ff have been estimated during March-May 2020 (during the COVID-19 outbreak) and March-May 2019 at a semiarid region of Agra over the Indo-Gangetic basin region. The daily mean mass concentration of BC in 2020 and 2019 was 3.9 and 6.9 µg m-3, respectively. The high monthly mean mass concentration of BC was found to be 4.7, 3.4 and 3.3 µg m-3 in Mar-2020, Apr-2020, and May-2020, respectively, whereas in Mar-2019, Apr-2019, and May-2019 was 7.7, 7.5 and 5.4 µg m-3, respectively. The absorption coefficient (babs) and absorption angstrom exponent (AAE) of black carbon were calculated. The highest mean AAE was 1.6 in the year 2020 (Mar-May 2020) indicating the dominance of biomass burning. The mean mass concentration of fossil fuel (BC)ff and biomass burning (BC)bb is 3.4 and 0.51 µg m-3, respectively, in 2020 whereas 6.4 and 0.73 µg m-3, respectively, in 2019. The mean fraction contribution of BC with fossil fuel (BC)ff was 82.1 ± 13.5% and biomass burning (BC)bb was 17.9 ± 4.3% in 2020, while in 2019, fossil fuel (BC)ff was 86.7 ± 13.5% and biomass burning (BC)bb was 13.3 ± 6.7%. The population-weighted mean concentration of BC, fossil fuel (BC)ff, and biomass burning (BC)bb has been calculated. The health risk assessment of BC has been analyzed in the form of attributable relative risk factors and attributed relative risk during the COVID-19 outbreak using AirQ + v.2.0 model. The attributable relative risk factors of BC were 20.6% in 2020 and 29.4% in 2019. The mean attributed relative risk per 10,000,000 populations at 95% confidence interval (CI) due to BC was 184.06 (142.6-225.2) in 2020 and 609.06 (418.3-714.6) in 2019. The low attributed factor and attributed relative risk in 2020 may be attributed to improvements in air quality and a fall in the emission of BC. In 2020, due to the COVID-19 pandemic, the whole country faced the biggest lockdown, ban of the transportation of private vehicles, trains, aircraft, and construction activities, and shut down of the industry leading to a fall in the impact of BC on human health. Overall, this was like a blessing in disguise. This study will help in future planning of mitigation and emission control of air pollutants in large and BC in particular. It only needs a multipronged approach. This study may be like torch bearing to set path for mitigation of impacts of air pollution and improvement of air quality.

2.
Curr Res Microb Sci ; 3: 100162, 2022.
Article in English | MEDLINE | ID: covidwho-2007638

ABSTRACT

Corona virus is pandemic and responsible for more than 5.6 million deaths. It was observed that its severity was reported in varied ways in different countries and even in different states of India. This variation was critically evaluated in the area with high contamination of Arsenic (As) to understand the arsenic toxicity and Covid epidemiology and associated health effects in the human population. It was reported that the area with low arsenic contamination has a very high incidence rate of Corona infection in the world. Even in the Indian scenario, high As-contaminated states like West Bengal, Jharkhand and Bihar, the incidence rate is 1.994%, 1.114% and 0.661%, respectively. In contrast, states with the least arsenic contamination have a very high corona incidence rate like 6.308, 17.289 and 4.351, respectively. It was evident that Arsenic inhibits the RdRp complex, which leads to the inhibition of viral genome replication. The PAMP associated pathway was activated by Arsenic and effectively bound with viral spike proteins leading to effective clearance of virus through activation of TNF alpha and IL-1. It finally leads to increased production of IgE, IgG and IGA. Arsenic also enhances inflammatory response against the virus through increased production of cytokine. The high arsenic level also induces apoptosis in viral infected cells through Bax/Bak pathway. It activates cytochrome-c and caspase-3 activity, inducing apoptosis in viral infected cells through PARP activation in the nucleus. These combined findings suggest that high arsenic contamination causes replication inhibition, activates an inflammatory response, increases antibody production, and finally leads to apoptosis through the mitochondrial pathway. People residing in arsenic hit areas are at a very low threat of corona infection.

3.
Asia Pac J Atmos Sci ; 57(4): 741-756, 2021.
Article in English | MEDLINE | ID: covidwho-1064622

ABSTRACT

The present paper designed to understand the variations in the atmospheric pollutants viz. PM10, PM2.5, SO2, NO2, and CO during the COVID-19 pandemic over eight most polluted Indian cities (Mumbai, Delhi, Bangalore, Hyderabad, Lucknow, Chandigarh, Kolkata, and Ahmedabad). A significant reduction in the PM2.5 (63%), PM10 (56%), NO2 (50%), SO2 (9%), and CO (59%) were observed over Major Dhyan Chand Stadium. At Chhatrapati Shivaji International Airport, a decline of 44% in PM2.5 and 50% in PM10 was seen just a week during the initial phase of the lockdown. Gaseous pollutants (NO2, SO2 & CO) dropped up-to 36, 16, and 41%, respectively. The Air Quality Index (AQI) shows a dramatic change from 7% to 67% during observation at Chandigarh and Ballygunge during the inspection. Whereas, Ahmedabad, Worli, Income Tax Office, Talkatora, Lalbagh, and Ballygaunge have showed a significant change in AQI from 25.76% to 68.55%. However, Zoo Park, CST, Central School, and Victoria show relatively low variation in AQI in the range of 3.0% to 14.50% as compare to 2019 after lockdown. Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) analysis suggested that long range transportation of pollutants were also a part and parcel contributing to changes in AQI which were majorly coming from the regions of Iran, Afghanistan, Saudi Arabia, as well as a regional grant from Indian Gangatic plains and Delhi Non-capital region.

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